Cutaneous Lesions Following Inoculation of Live Culture of Leishmania Donovani in Man

produced in man by inoculation of cultures of Leishmania tropica. Cutaneous inoculation of Leishmania donovani from spleen puncture material from a case of kala-azar, however, is reported to have ' apparently produced kala-azar in a man' but on two occasions accidental inoculation of spleen puncture material from cases of kala-azar was without any effect (Napier, 1927). Recently, Terry et al. (1950) have reported'a case of laboratory infection with Leishmania donovani, probably caused by the bite of leishmania infected animals. The lesions produced were swelling of a finger and regional epitrochlear and axillary adenopathy and there was no evidence of systemic infection. The lesions disappeared following antimony therapy. In this paper we present the brief notes of a case in which intradermal injection of leptomonads from a culture of Leishmania donovani was followed by the development of cutaneous nodules at the sites of inoculation.